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DTSTART;TZID=America/New_York:20220707T090000
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DTSTAMP:20260413T205231
CREATED:20240215T094540Z
LAST-MODIFIED:20240229T085211Z
UID:10002727-1657184400-1657188000@cmsa.fas.harvard.edu
SUMMARY:The phenotype of the last universal common ancestor and the evolution of complexity
DESCRIPTION:Interdisciplinary Science Seminar\n\n\n\n\n\nSpeaker: Fouad El Baidouri\, Broad Institute \nTitle: The phenotype of the last universal common ancestor and the evolution of complexity \nAbstract: A fundamental concept in evolutionary theory is the last universal common ancestor (LUCA) from which all living organisms originated. While some authors have suggested a relatively complex LUCA it is still widely assumed that LUCA must have been a very simple cell and that life has subsequently increased in complexity through time. However\, while current thought does tend towards a general increase in complexity through time in Eukaryotes\, there is increasing evidence that bacteria and archaea have undergone considerable genome reduction during their evolution. This raises the surprising possibility that LUCA\, as the ancestor of bacteria and archaea may have been a considerably complex cell. While hypotheses regarding the phenotype of LUCA do exist\, all are founded on gene presence/absence. Yet\, despite recent attempts to link genes and phenotypic traits in prokaryotes\, it is still inherently difficult to predict phenotype based on the presence or absence of genes alone. In response to this\, we used Bayesian phylogenetic comparative methods to predict ancestral traits. Testing for robustness to horizontal gene transfer (HGT) we inferred the phenotypic traits of LUCA using two robust published phylogenetic trees and a dataset of 3\,128 bacterial and archaeal species. \nOur results depict LUCA as a far more complex cell than has previously been proposed\, challenging the evolutionary model of increased complexity through time in prokaryotes. Given current estimates for the emergence of LUCA we suggest that early life very rapidly evolved cellular complexity.
URL:https://cmsa.fas.harvard.edu/event/iss_7722/
CATEGORIES:Interdisciplinary Science Seminar
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DTSTART;TZID=America/New_York:20220707T103000
DTEND;TZID=America/New_York:20220707T123000
DTSTAMP:20260413T205231
CREATED:20240215T100432Z
LAST-MODIFIED:20240229T091815Z
UID:10002737-1657189800-1657197000@cmsa.fas.harvard.edu
SUMMARY:Anomalies\, dynamics and phases in strongly-coupled chiral gauge theories: Recent developments
DESCRIPTION:Speaker: Kenichi Konishi (UNIPI.IT) \nTitle: Anomalies\, dynamics and phases in strongly-coupled chiral gauge theories: Recent developments \nAbstract: After many years of efforts\, still very little is known today about the physics of strongly-coupled chiral gauge theories in four dimensions\, in spite of an important role they might play in the physics of fundamental interactions beyond the standard SU(3)xSU(2)xU(1) model. This is in stark contrast with the vectorlike gauge theories for which we have many solid results\, thanks to some exact theorems\, to the lattice simulation studies\, to the Seiberg-Witten exact solution of N=2 supersymmetric gauge theories\, and last\, but not the least\, to the real-world strong-interaction phenomenology and experimental tests of Quantum Chromodynamics. \nThe purpose of this seminar is to discuss the results of our recent efforts to improve the understanding of the strongly-coupled chiral gauge theories. Among the main tools of analysis are the consideration of anomalies. We use both the conventional ’t Hooft anomaly-matching ideas\, and new\, more stringent constraints coming from the generalized anomalies involving some higher-form symmetries. Also\, the so-called strong anomalies\, little considered in the context of chiral gage theories\, are found to carry significant implications. \nAs the playground we study several classes of SU(N) gauge theories\, the so-called Bars-Yankielowicz models\, the generalized Georgi-Glashow models\, as well as a few other simple theories with the fermions in complex\, anomaly-free representations of the color SU(N). \nColor-flavor-locked dynamical Higgs phase and dynamical Abelianization\, emerge\, among others\, as two particularly interesting possible phases the system can flow into in the infrared\, depending on the matter fermion content of the model.
URL:https://cmsa.fas.harvard.edu/event/qm_7722/
LOCATION:Virtual
CATEGORIES:Quantum Matter
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