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DTSTART;TZID=America/New_York:20230914T130000
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DTSTAMP:20260701T171647
CREATED:20240223T111752Z
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SUMMARY:Frustration-free states of cell fate networks: the case of the epithelial-mesenchymal transition
DESCRIPTION:Active Matter Seminar\n\n\nSpeaker: Herbert Levine (Northeastern)\n\nTitle: Frustration-free states of cell fate networks: the case of the epithelial-mesenchymal transition\n\nAbstract: Cell fate decisions are made by allowing external signals to govern the steady-state pattern adopted by networks of interacting regulatory factors governing transcription and translation. One of these decisions\, of importance for both developmental processes and for cancer metastasis\, is the epithelial-mesenchymal transition (EMT). In this talk\, we will argue that these biological networks have highly non-generic interaction structures such that they allow for phenotypic states with very low frustration\, i.e. where most interactions are satisfied. This property has important consequences for the allowed dynamics of these systems.
URL:https://cmsa.fas.harvard.edu/event/am-91423/
LOCATION:CMSA Room G10\, CMSA\, 20 Garden Street\, Cambridge\, MA\, 02138\, United States
CATEGORIES:Active Matter Seminar
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DTSTART;TZID=America/New_York:20230928T130000
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CREATED:20240223T072654Z
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SUMMARY:Strongly driven mixtures and membranes: Out of equilibrium surprises 
DESCRIPTION:Active Matter Seminar\n\n\nSpeaker: Max Lavrentovich\, Worcester State University \nTitle: Strongly driven mixtures and membranes: Out of equilibrium surprises \nAbstract: The more prosaic cousin of active matter\, driven inactive matter\, is still full of unexpected phenomena. I will discuss two projects involving two seemingly mundane systems\, a phase-separating colloidal mixture and a lipid membrane\, which demonstrate counterintuitive properties when driven out of equilibrium. We will see that the phase separating mixture\, when driven by a uniform force\, develops (in simulations) an intriguing pattern with a characteristic length scale set by the magnitude of the drive. We will look at some theoretical approaches to understanding the pattern formation and possible experimental realizations. The membrane\, when driven by an oscillatory electric field\, develops (in experiments) a long-lived metastable state with a decreased capacitance and increased dissipation. This state may have implications for neuronal processing and memory formation.
URL:https://cmsa.fas.harvard.edu/event/am-92823/
LOCATION:CMSA Room G10\, CMSA\, 20 Garden Street\, Cambridge\, MA\, 02138\, United States
CATEGORIES:Active Matter Seminar
ATTACH;FMTTYPE=image/png:https://cmsa.fas.harvard.edu/media/CMSA-Active-Matter-Seminar-09.28.23.png
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