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SUMMARY:Nuclear chromodynamics: non-equilibrium phase transition in the nucleus of a living cell
DESCRIPTION:Active Matter Seminar\n\n\nSpeaker: Alexander Grosberg (NYU)\n\nTitle: Nuclear chromodynamics: non-equilibrium phase transition in the nucleus of a living cell \nAbstract: Nucleus of a living cell houses a cell genome – a polymer called chromatin\, which is a functional form of DNA.  It is very long\, e.g.\, 2 meters long for every human cell.  Nucleus is also an arena of incessant energy-driven activity.  Experiments show that chromatin undergoes large scale motions sustained over long times of order seconds.  In the talk\, after reviewing the phenomenology\, I will show how these flows may arise due to a phase transition in which chromatin-driving motors\, such as RNA polymerase\, form a polar (“ferromagnetic”) order controlled by hydrodynamic interactions.  The talk is based on the joint work with I.Eshghi and A.Zidovska.
URL:https://cmsa.fas.harvard.edu/event/am-11923/
LOCATION:CMSA Room G10\, CMSA\, 20 Garden Street\, Cambridge\, MA\, 02138\, United States
CATEGORIES:Active Matter Seminar
ATTACH;FMTTYPE=image/png:https://cmsa.fas.harvard.edu/media/CMSA-Active-Matter-Seminar-11.09.23.png
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