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DTSTAMP:20240122T172011Z
CREATED:20230824T175941Z
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SUMMARY:Dynamic and multicolor electron microscopy
DESCRIPTION:Active Matter Seminar\n\n\nSpeaker: Max Prigozhin (Harvard) \nTitle: Dynamic and multicolor electron microscopy \nAbstract: My lab is developing biophysical methods to achieve multicolor and dynamic biological imaging at the molecular scale. Our approach to capturing the dynamics of cellular processes involves cryo-vitrifying samples after known time delays following stimulation using custom cryo- plunging and high-pressure freezing instruments. To achieve multicolor electron imaging\, we are exploring the property of cathodoluminescence—optical emission induced by the electron beam. We are developing nanoprobes (“cathodophores”) that will be used as luminescent protein tags in electron microscopy. We are applying these new methods to study G-protein- coupled receptor signaling and to visualize the formation of biomolecular condensates.
URL:https://cmsa.fas.harvard.edu/event/am-111722/
LOCATION:CMSA Room G10\, CMSA\, 20 Garden Street\, Cambridge\, MA\, 02138\, United States
CATEGORIES:Active Matter Seminar
ATTACH;FMTTYPE=image/png:https://cmsa.fas.harvard.edu/media/CMSA-Active-Matter-Seminar-11.17.22.png
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