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DTSTART;TZID=America/New_York:20190327T171500
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DTSTAMP:20240514T181829Z
CREATED:20240212T110407Z
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SUMMARY:Hyperbolic geometry of the olfactory space
DESCRIPTION:Speaker: Tatyana Sharpee (Salk Institute for Biological Studies) \nTitle: Hyperbolic geometry of the olfactory space \nAbstract: The sense of smell can be used to avoid poisons or estimate a food’s nutrition content because biochemical reactions create many by-products. Thus\, the presence of certain bacteria in the food becomes associated with the emission of certain volatile compounds. This perspective suggests that it would be convenient for the nervous system encode odors based on statistics of their co-occurrence within natural mixtures rather than based on the chemical structure per se. I will discuss how this statistical perspective makes it possible to map odors to points in a hyperbolic space. Hyperbolic coordinates have a long but often underappreciated history of relevance to biology. For example\, these coordinates approximate distance between species computed along dendograms\, and more generally between points within hierarchical tree-like networks. We find that these coordinates\, which were generated purely based on the statistics of odors in the natural environment\, provide a contiguous map of human odor pleasantness. Further\, a separate analysis of human perceptual descriptions of smells indicates that these also generate a three dimensional hyperbolic representation of odors. This match in geometries between natural odor statistics and human perception can help to minimize distortions that would otherwise arise when mapping odors to perception. We identify three axes in the perceptual space that are aligned with odor pleasantness\, its molecular boiling point and acidity. Because the perceptual space is curved\, one can predict odor pleasantness by knowing the coordinates along the molecular boiling point and acidity axes. \n  \n 
URL:https://cmsa.fas.harvard.edu/event/3-27-2019-colloquium/
LOCATION:CMSA\, 20 Garden Street\, Cambridge\, MA\, 02138\, United States
CATEGORIES:Colloquium
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