Abstract: In this talk we will discuss the interaction between magnetic monopoles and massless fermions. In the 1980’s Callan and Rubakov showed that in the simplest example and that fermion-monopole interactions catalyze proton decay in GUT completions of the standard model. Here we will explain how fermions in general representations interact with general spherically symmetric monopoles and classify the types of symmetries that are broken: global symmetries with ABJ-type anomalies.