Active structures and flows in living cells

12/07/2023 1:00 pm - 2:00 pm
CMSA Room G10
Address: CMSA, 20 Garden Street, Cambridge, MA 02138 USA
Active Matter Seminar

Speaker: Michael Shelley (Flatiron)

Title: Active structures and flows in living cells

Abstract: Flows in the fluidic interior of living cells can serve biological function or act as signatures of how intracellular forces are exerted. I’ll discuss examples of each. One is understanding the emergence of cell-spanning vortical flows in large developing egg cells, while the other arises in studying the nature of force transduction in single cell embryos moving towards their first cell division. Both involve the cytoskeleton, that set of polymers, cross-linkers, and molecular motors that underlie much of the active mechanics within cells, and has led to the development of new coarse-grained active matter models and novel instabilities.