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The Role of Orientational Order in Development

March 30, 2023 @ 1:00 pm - 2:00 pm

Active Matter Seminar

Speaker: Mark Bowick, Kavli Institute for Theoretical Physics, UCSB

Title: The Role of Orientational Order in Development

Abstract: Morphogenesis, the process through which genes generate form, establishes tissue scale order as a template for constructing the complex shapes of the body plan. The extensive growth required to build these ordered substrates is fueled by cell proliferation, which, naively, should disrupt order. Understanding how active morphogenetic mechanisms couple cellular and mechanical processes to generate order remains an outstanding question in animal development. I will review the statistical mechanics of orientational order and discuss the observation of a fourfold orientationally ordered phase (tetratic) in the model organism Parhyale hawaiensis. I will also discuss theoretical mechanisms for the formation of orientational order that require both motility and cell division, with support from self-propelled vertex models of tissue. The aim is to uncover a robust, active mechanism for generating global orientational order in a non-equilibrium system that then sets the stage for the development of shape and form.

Details

Date:
March 30, 2023
Time:
1:00 pm - 2:00 pm
Event Category:

Venue

CMSA Room G10
CMSA, 20 Garden Street
Cambridge, MA 02138 United States
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Phone:
6174967132