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Interacting Active Matter
February 2, 2023 @ 1:00 pm - 2:00 pm
![CMSA Active Matter Seminar 02.02.23](https://cmsa.fas.harvard.edu/media/CMSA-Active-Matter-Seminar-02.02.23.png)
Speaker: Amin Doostmohammadi, Niels Bohr Institute, University of Copenhagen
Title: Interacting Active Matter
Abstract: I will focus on the interaction between different active matter systems. In particular, I will describe recent experimental and modeling results that reveal how interaction forces between adhesive cells generate activity in the cell layer and lead to a potentially new mode of phase segregation. I will then discuss mechanics of how cells use finger-like protrusions, known as filopodia, to interact with their surrounding medium. First, I will present experimental and theoretical results of active mirror-symmetry breaking in subcellular skeleton of filopodia that allows for rotation, helicity, and buckling of these cellular fingers in a wide variety of cells ranging from epithelial, mesenchymal, cancerous and stem cells. I will then describe in-vivo experiments together with theoretical modeling showing how during embryo development specialized active cells probe and modify other cell layers and integrate within an active epithelium.